Publications

Dumartin L, Quemener C, Laklai H, Herbert J, Bicknell R, Bousquet C, Pyronnet S, Castronovo V, Schilling MK, Bikfalvi A., Hagedorn M. (2010) Netrin-1 mediates essential events of pancreatic adenocarcinoma progression by acting on tumor and endothelial cells. Gastroenterology, 138(4):1595-606.

Dedieu S, Canron X, Rezvani H, Bouchecareilh M, Mazurier F, Sinisi R, Zanda M, Moenner M, Bikfalvi A, North S. (2010) The cytoprotective drug amifostine modifies both expression and activity of the pro- angiogenic factor VEGF-A. BMC Medicine, 24;8:19.

Kraeber-Bodéré F, Bodet-Milin C, Niaudet C, Saï-Maurel C, Moreau A, Faivre-Chauvet A, Thomare P, Deleris G, Estieu-Gionnet K, Bikfalvi A, Barbet J, Paris F. (2010) Comparative toxicity and efficacy of combined radioimmunotherapy and antiangiogenic therapy in carcinoembryonic antigen-expressing medullary thyroid cancer xenograft. J Nucl Med. 51(4):624-31.

Verpelli C, Bertani G, Cea V, Patti M, Bikfalvi A, Bello L, Sala C (2010)Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma. PLoS One, 5(10):e13710

Soulet F, Kilarski WW, Antczak P, Herbert J, Bicknell R, Falciani F, Bikfalvi A. (2010) Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model. BMC Genomics, 11:495.

Aidoudi S, Bikfalvi A. (2010) Interaction of PF4 (CXCL4) with the vasculature: a role in atherosclerosis and angiogenesis. Thromb Haemost., 104(5):941-8

Auf G, Jabouille A, Guérit S, Pineau R, Delugin M, Bouchecareilh M, Magnin N, Favereaux A, Maitre M, Gaiser T, von Deimling A, Czabanka M, Vajkoczy P, Chevet E, Bikfalvi A, Moenner M. (2010) Inositol- requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Proc Natl Acad Sci U S A., 107(35):15553-8.

Dubrac A, Quemener C, Lacazette E, Lopez F, Zanibellato C, Wu WG, Bikfalvi A, Prats H. (2010) Functional divergence between two chemokines is conferred by single amino acid change.Blood. Blood. 116(22):4703-11 (A. Bikfalvi corresponding author and Co-PI).

Cavill R, Sidhu JK, Kilarski W, Javerzat S, Hagedorn M, Ebbels TM, Bikfalvi A, Keun HC. (2010) A combined metabonomic and transcriptomic approach to investigate metabolism during development in the chick chorioallantoic membrane. J Proteome Res. 9(6):3126-34] (A. Bikfalvi corresponding author and Co- PI).

Bikfalvi A, Moenner M, Javerzat S, North S, Hagedorn M. (2011) Inhibition of angiogenesis and the angiogenesis/invasion shift. Biochem Soc Trans. 39(6):1560-4

Ligi I, Simoncini S, Tellier E, Frizera Vassallo P, Sabatier F, Guillet B, Lamy E, Sarlon G, Quemener C, Bikfalvi A, Marcelli M, Pascal A, Dizier B, Simeoni U, Dignat-George F, Anfosso F (2011) A switch toward angiostatic gene expression impairs the angiogenic properties of endothelial progenitor cells in low birth weight pre-term infants Blood., 118(6):1699-709.

Gupta R, Stincone A, Antczak P, Durant S, Bicknell R, Bikfalvi A, Falciani F. (2011) A Computational framework for gene regulatory network inference that combines multiple methods and datasets. BMC Syst Biol., 5:52.

Trevino V, Tadesse MG, Vannucci M, Al-Shahrour F, Antczak P, Durant S, Bikfalvi A, Dopazo J, Campbell MJ, Falciani F. (2011) Analysis of normal-tumour tissue interaction in tumours: prediction of prostate cancer features from the molecular profile of adjacent normal cells. PLoS One, 6(3):e16492.

Larrieu-Lahargue F, Welm AL, Bouchecareilh M, Alitalo K, Li DY, Bikfalvi A, Auguste P. (2012) Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis PLoS One, 7(6):e39540. (AB PA Co-PI, AB corresponding author)

Bikfalvi A. (2012) Angiogenesis and invasion in cancer. Handb Clin Neurol. 104:35-43.

Bernard H, Garmy-Susini B, Ainaoui N, Van Den Berghe L, Peurichard A, Javerzat S, Bikfalvi A, Lane DP, Bourdon JC, Prats AC. (2013) The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression. Oncogene, 32(17):2150-60.

Auf G, Jabouille A, Delugin M, Guérit S, Pineau R, North S, Platonova N, Maitre M, Favereaux A, Vajkoczy P, Seno M, Bikfalvi A, Minchenko D, Minchenko O, Moenner M. (2013) High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor. BMC Cancer, 13:597.

Exertier P, Javerzat S, Wang B, Franco M, Herbert J, Platonova N, Winandy M, Pujol N, Nivelles O, Ormenese S, Godard V, Becker J, Bicknell R, Pineau R, Wilting J, Bikfalvi A, Hagedorn M. (2013) Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5. Oncotarget, 4(12):2302-16. (AB et MH Co-Pi’s)

Billottet C, Quemener C, Bikfalvi A. (2013) CXCR3, a double-edged sword in tumor progression and angiogenesis. Biochim Biophys Acta., 1836(2):287-95.

Ayoub E, Hall A, Scott AM, Chagnon MJ, Miquel G, Hallé M, Noda M, Bikfalvi A, Tremblay ML. (2013) Regulation of the Src kinase-associated phosphoprotein 55 homologue by the protein tyrosine phosphatase PTP-PEST in the control of cell motility. J Biol Chem. 88(36):25739-48.

Prats AC, Van den Berghe L, Rayssac A, Ainaoui N, Morfoisse F, Pujol F, Legonidec S, Bikfalvi A, Prats H, Pyronnet S, Garmy-Susini B. (2013) CXCL4L1-fibstatin cooperation inhibits tumor angiogenesis, lymphangiogenesis and metastasis. Microvasc Res. 89: 25-33.

Soulet F, Kilarski WW, Roux-Dalvai F, Herbert JM, Sacewicz I, Mouton-Barbosa E, Bicknell R, Lalor P, Monsarrat B, Bikfalvi A. (2013) Mapping the extracellular and membrane proteome associated with the vasculature and the stroma in the embryo. Mol Cell Proteomics. 12(8):2293-312.

Kuo JH, Chen YP, Liu JS, Dubrac A, Quemener C, Prats H, Bikfalvi A, Wu WG, Sue SC. (2013) Alternative C-terminal helix orientation alters chemokine function: structure of the anti-angiogenic chemokine, CXCL4L1. J Biol Chem., 288(19):13522-33.

Platonova N, Miquel G, Regenfuss B, Taouji S, Cursiefen C, Chevet E, Bikfalvi A. (2013) Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1. Blood, 121(7):1229-37.

Fergelot P, Bernhard JC, Soulet F, Kilarski WW, Léon C, Courtois N, Deminière C, Herbert JM, Antczak P, Falciani F, Rioux-Leclercq N, Patard JJ, Ferrière JM, Ravaud A, Hagedorn M, Bikfalvi A. (2013) The experimental renal cell carcinoma model in the chick embryo. Angiogenesis, 16(1):181-94.

Minchenko OH, Tsuchihara K, Minchenko DO, Bikfalvi A, Esumi H. (2014) Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells. World J Gastroenterol. 20(38):13705-17.

Platonova N, Miquel G, Chiu LY, Taouji S, Moroni E, Colombo G, Chevet E, Sue SC, Bikfalvi A. (2014) Dimerization capacities of FGF2 purified with or without heparin-affinity chromatography. PLoS One, 9(10):e110055.

Sfaxi F, Scamuffa N, Lalou C, Ma J, Metrakos P, Siegfried G, Ragg H, Bikfalvi A, Calvo F, Khatib AM. (2014) Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases. Oncotarget 5(12):4195-210.

Guérit S, Allain AE, Léon C, Cazenave W, Ferrara N, Branchereau P, Bikfalvi A. (2014) VEGF modulates synaptic activity in the developing spinal cord. Dev Neurobiol. 74(11):1110-22.

Ligi I, Simoncini S, Tellier E, Grandvuillemin I, Marcelli M, Bikfalvi A, Buffat C, Dignat-George F, Anfosso F, Simeoni U. (2014) Altered angiogenesis in low birth weight individuals: a role for anti- angiogenic circulating factors. J Matern Fetal Neonatal Med. 27(3):233-8.

Baud J, Lomri A, Graber D, Bikfalvi A. (2015) The therapeutic response in Gorham’s syndrome to the beta- blocking agent propranolol is correlated to VEGF-A, but not to VEGF-C or FLT1 expression. BMC Res Notes ; 8:333.

Clarke K, Daubon T, Turan N, Soulet F, Mohd Zahari M, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK, Bjerkvig R, Bicknell R, Hotchin NA, Bikfalvi A*, Falciani F*. (2015) Inference of Low and High- Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer. PLoS Genet. 11(7):e1005325. (AB et FF Co-Pis and corresponding authors)

Minchenko OH, Tsymbal DO, Minchenko DO, Kovalevska OV, Karbovskyi LL, Bikfalvi A. (2015) Inhibition of ERN1 signaling enzyme affects hypoxic regulation of the expression of E2F8, EPAS1, HOXC6, ATF3, TBX3 and FOXF1 genes In U87 glioma cells. Ukr Biochem J. 87(2):76-87.

Vaudel M, Barsnes H, Bjerkvig R, Bikfalvi A, Selheim F, Berven FS, Daubon T. (2016) Practical Considerations for Omics Experiments in Biomedical Sciences. Curr Pharm Biotechnol. 17(1):105-14.

Jabouille A, Delugin M, Pineau R, Dubrac A, Soulet F, Lhomond S, Pallares-Lupon N, Prats H, Bikfalvi A, Chevet E, Touriol C, Moenner M. (2015) Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity. Oncotarget. 6(28):24922-34.

Baratchart E, Benzekry S*, Bikfalvi A*, Colin T*, Cooley LS, Pineau R, Ribot EJ, Saut O, Souleyreau W. (2015) Computational Modelling of Metastasis Development in Renal Cell Carcinoma. PLoS Comput Biol. 11(11):e1004626. (Authors in alphabetic order, Co-PI’s AB, TC, SB)

Quemener C, Baud J, Boyé K, Dubrac A, Billottet C, Soulet F, Darlot F, Dumartin L, Sire M, Grepin R, Daubon T, Rayne F, Wodrich H, Couvelard A, Pineau R, Schilling M, Castronovo C, Sue SC, Clarke K, Lomri AR, Khatib AM, Hagedorn M, Prats H, Bikfalvi A. CXCL4 chemokines, CXCR3 and Pancreatic Cancer: a dual Role in Tumor Angiogenesis and Invasion ?  Cancer Res. 2016 Nov 15;76(22):6507-6519

Dufies M, Giuliano S, Ambrosetti D, Claren A, Ndiaye PD, Mastri M, Moghrabi W, Cooley LS, Ettaiche M, Chamorey E, Parola J, Vial V, Lupu-Plesu M, Bernhard JC, Ravaud A, Borchiellini D, Ferrero JM, Bikfalvi A, Ebos JM, Khabar KS, Grépin R, Pagès G.Sunitinib Stimulates Expression of VEGFC by Tumor Cells and Promotes Lymphangiogenesis in Clear Cell Renal Cell Carcinomas. Cancer Res. 2017 Mar 1;77(5):1212-1226.

Alessandri K, Andrique L, Feyeux M, Bikfalvi A, Nassoy P, Recher G. All-in-one 3D printed microscopy chamber for multidimensional imaging, the UniverSlide.Sci Rep. 2017 Feb 10;7:42378.

Bikfalvi A History and conceptual developments in vascular biology and angiogenesis research: a personal view.Angiogenesis. 2017 Nov;20(4):463-478

Dufies M, Giuliano S, Viotti J, Borchiellini D, Cooley LS, Ambrosetti D, Guyot M, Ndiaye PD, Parola J, Claren A, Schiappa R, Gal J, Frangeul A, Jacquel A, Cassuto O, Grépin R, Auberger P, Bikfalvi A, Milano G, Escudier B, Rioux-Leclercq N, Porta C, Negrier S, Chamorey E, Ferrero JM, Pagès G. CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas. Br J Cancer. 2017 Sep 26;117(7):947-953.

Boyé K, Billottet C, Pujol N, Alves ID, Bikfalvi A.Ligand activation induces different conformational changes in CXCR3 receptor isoforms as evidenced by plasmon waveguide resonance (PWR).Sci Rep. 2017 Sep 6;7(1):10703.

Ravaud A, Gomez-Roca C, Picat MQ, Digue L, Chevreau C, Gimbert A, Chauzit E, Sitta R, Cornelis F, Asselineau J, Aziza R, Daste A, Quemener C, Baud J, Bikfalvi A, Pedenon-Périchout D, Doussau A, Molimard M, Delord JP.Phase I study of axitinib and everolimus in metastatic solid tumours and extension to metastatic renal cell carcinoma: Results of EVAX study.Eur J Cancer. 2017 Nov;85:39-48

Boyé K, Pujol N, D Alves I, Chen YP, Daubon T, Lee YZ, Dedieu S, Constantin M, Bello L, Rossi M, Bjerkvig R, Sue SC, Bikfalvi A*, Billottet C*.The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors. Nat Commun. 2017 Nov 17;8(1):1571. AB et CB Co-Corresponding authors

Kilarski WW, Herbert J, Bikfalvi A. Methods for Mapping the Extracellular and Membrane Proteome in the Avian Embryo, and Identification of Putative Vascular Targets or Endothelial Genes.Methods Mol Biol. 2018;1722:31-56

Rousseau, B., Dubayle, D., Sennlaub, F., Jeanny, J.-C., Costet, P., Bikfalvi, A., and Javerzat, S. (2000). Neural and angiogenic defects in eyes of transgenic mice expressing a dominant-negative FGF receptor in the pigmented cells. Exp. Eye Res. , 71 : 395-404.

Hagedorn M, Bikfalvi A. (2000) Target molecule for anti-angiogenesis therapy : from basic research to clinical trials. Critical Reviews in Oncology Hematology, 34 : 89-110.

Hagedorn M., Zilberberg L., Lozano R., Cuevas P., Canron X., Redondo-Horcajo M., Gimenez-Gallego G., and Bikfalvi A. (2001) A short peptide domain of platelet factor 4 blocks angiogenic key events induced by FGF-2. FASEB J. published online Jan 5, 2001, 10.1096/fj.00-0285fje.

M. Hagedorn, L. Zilberberg, R. M. Lozano, P. Cuevas, X. Canron, M. Redondo-Horcajo, G. Gimenez- Gallego, and A. Bikfalvi (2001) A short peptide domain of platelet factor 4 blocks angiogenic key events induced by FGF-2. FASEB J 15 (3) : 550-552.

Auguste P, Demirkan B. Gürsel DB, Lemière S., Reimers D., Cuevas P, Carceller F, Di Santo JP., and Bikfalvi A.(2001) Inhibition of FGF/FGFR activity in glioma cells impedes tumor growth by both, angiogenesis-dependent and independent mechanisms. Cancer Research, 61, 1717-1726.

Lozano R., Jimenez M. A., Redondo-Horciao M., Zilberberg, L., Cuevas P., Bikfalvi, A. Roco M., Gimenez- Gallego G. (2001) Solution structure and interaction with basic and acidic fibroblast growth factor of a 3 kDa human platelet-factor-4 fragment with antiangiogenic activity. J Biol Chem, 276(38):35723-35734.

Bello L, Carrabia G, Giussani C, Lucini V, Cerutti F, Scaglione F, Landre J, Pluderi M, Tomei G, Villani R, Carroll R, Black P, Bikfalvi A (2001) Low-dose chemotherapy combined with antiangiogenic drug reduces human glioma growth in vivo. Cancer Res, 61(20):7501-6.

Bello L, Lucini V, Carrabba G, Giussani C, Machluf M, Pluderi M, Nikas D, Zhang J, Tomei G, Villani RM, Carroll RS, Bikfalvi A, Black PM. (2001) Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2. Cancer Res, 61(24):8730-6.

Bello L, Giussani C, Carrabba G, Pluderi M, Lucini V, Pannacci M, Caronzolo D, Tomei G, Villani R, Scaglione F, Carroll RS, Bikfalvi A. (2002) Suppression of malignant glioma recurrence in a newly developed animal model by fragments of endogenous inhibitors. Clinical Cancer Res; 8(11):3539-48.

Bello L, Carroll R,Giussani C., Carrabba G. ,Pluderi M., Pannac M., Tomei G, Villani R , Bikfalvi A. , McL Black P (2003) A specific avb3 integrin inhibitor reduces glioma growth in vivo. Neurosurgery 52(1):177-85 Javerzat S, P. Auguste, A. Bikfalvi (2002) The role of fibroblast growth factors in vascular development. Trends in Molecular Medicine ;8(10):483-9.

Bikfalvi A. and R. Bicknell (2002) Recent advances in angiogenesis, anti-angiogenesis and vascular targeting. Trends in Pharmacological Sciences ;23(12): 576-82.

Bikfalvi A. and Gimenez-Gallego G (2003) The control of angiogenesis and tumor invasion by platelet factor-4 and platelet factor-4-derived molecules Semin Thromb Hemost. 2004 Feb;30(1):137-44

Hagedorn M., Zilberberg L., Wilting J., Canron X., Carrabba G., Giussiani C., Pluderi M., Bello l., Bikfalvi A. (2002) Domain swapping in a C-terminal fragment of platelet factor-4 generates potent angiogenesis inhibitors. Cancer Res ;62(23):6884-90.

Giussani C., Carrabba G. ,Pluderi M., Lucini V., Pannacci M., , Villani R , Bikfalvi A., Bello L. (2003) Local intracerebral delivery of endogenous inhibitors by osmotic minipumps effectively suppresses glioma growth in vivo. Cancer Res. 63(10):2499-505.

Rousseau B, Larrieu-Lahargue F, Bikfalvi A, Javerzat S. (2003) Involvement of fibroblast growth factors in choroidal angiogenesis and retinal vascularization.. Exp Eye Res. 77(2):147-156.

Auguste P, Javerzat S, Bikfalvi A. (2003) Regulation of vascular development by fibroblast growth factors. Cell Tissue Res. 314(1):157-66

Bikfalvi A. (2003) Tumor angiogenesis Bull Cancer.; 90(5):449-58

Zilberberg L, Shinkaruk S, Lequin O, Rousseau B, Hagedorn M, Costa F, Caronzolo D, Bahlke M, Canron X, Convert O, Lain G, Gionnet K, Goncalves M, Bayle M, Bello L, Chassaing G, Deleris G, Bikfalvi A.(2003) Structure and inhibitory effects on angiogenesis and tumor development of a new vascular endothelial growth inhibitor. J Biol Chem 278(37):35564-35573

Pluderi M, Lucini V, Caronzolo D, Pannacci M, Costa F, Carrabba G, Giussani C, Grosso S, Colleoni F, Scaglione F, Villani R, Bikfalvi A, Bello L. (2003) Long-term inhibition of glioma growth by systemic administration of human PEX. J Neurosurg Sci. 47(2):69-78.

Heidi Bompais; Jalila Chagraoui; Xavier Canron, , Mihaela Crisan; Xu Hui Liu; Aurora Anjo; Carine Tolla Le Port; Marylene Leboeuf; Pierre Charbord; Andreas Bikfalvi; Georges Uzan. (2003) Human endothelial cells derived from circulating progenitors display specific functional properties as compared to mature vessel wall endothelial cells. Blood. 103(7):2577-84

Bello L, Lucini V, Costa F, Pluderi M, Giussani C, Acerbi F, Carrabba G, Pannacci M, Caronzolo D, Grosso S, Shinkaruk S, Colleoni F, Canron X, Tomei G, Deleris G, Bikfalvi A. (2004) Combinatorial administration of molecules that simultaneously inhibit angiogenesis and invasion leads to increased therapeutic efficacy in mouse models of malignant glioma. Clin Cancer Res. 10(13):4527-37.

Bikfalvi A. Platelet factor 4: an inhibitor of angiogenesis. Semin Thromb Hemost. 2004 Jun;30(3):379-85. Hagedorn M., Balke M., Bloch W., Javerzat S., Rousseau B, Schmidt A., Kurtz H., Wilting J., Bikfalvi A. (2004) VEGF coordinates interaction of pericytes and endothelial cells during vasculogenesis and experimental angiogenesis. Dev Dyn, 230:23-33

Benoit Rousseau, Frédéric Larrieu-Lahargue, Fréderic Guilhem-Ducléon, Friedrich Beermann, Sophie Javerzat and Andreas Bikfalvi (2004) The tyrp1-Tag/tyrp1-FGFR1-DN bigenic mouse : A model for selective inhibition of tumor development, angiogenesis and invasion into the neural tissue by blockade of fibroblast growth factor (FGF) receptor activity Cancer Res. 64(7):2490-5.

Bikfalvi A. (2004) Recent developments in the inhibition of angiogenesis: examples from studies on platelet factor-4 and the VEGF/VEGFR system. Biochem.Pharmacol.; 68:1017-21.

Bello L, Giussani C, Carrabba G, Pluderi M, Costa F, Bikfalvi A. (2004) Angiogenesis and invasion in gliomas. Cancer Treat Res. 117:263-84.

Miraux S, Lemière S, Pineau R, Pluderi M, Canioni P, Franconi JM, Thudière E., Bello L, Bikfalvi A, Auguste P. (2004)Inhibition of FGF receptor activity in glioma implanted into the mouse brain. Angiogenesis. 2004;7(2):105-13. Corresponding author: A.Bikfalvi

Bikfalvi A. (2004) Le rôle du facteur plaquettaire 4 dans la régulation et l’inhibition de l’angiogenèse. Hématologie, 10 : 365-369

Auguste P, Lemiere S, Larrieu-Lahargue F, Bikfalvi A (2005) Molecular mechanisms of tumor vascularization. Crit Rev Oncol Hematol. 54(1):53-61

Hagedorn M, Javerzat S., Gilges D., Meyre A., de Lafarge B, Eichmann A. Bikfalvi A. (2005) Accessing key steps of human tumor progression in vivo using an avian embryo model. Proc. Natl. Acad Sci USA, 102 (5) : 643-1648

Benny O, Duvshani-Eshet M, Cargioli T, Bello L, Bikfalvi A, Carroll RS, Machluf M.(2005) Continuous delivery of endogenous inhibitors from poly(lactic-co-glycolic Acid) polymeric microspheres inhibits glioma tumor growth. Clin Cancer Res.11(2 Pt 1):768-76.

Goncalves M, Estieu-Gionnet K, Berthelot T, Lain G, Bayle M, Canron X, Betz N, Bikfalvi A, Deleris G. (2005) Design, synthesis, and evaluation of original carriers for targeting vascular endothelial growth factor receptor interactions. Pharm Res. 22(8):1411-21

Javerzat S, Bikfalvi A, Hagedorn M. (2005) [Understanding in treating gliomas: an adequate experimental model for each question] Bull Cancer. 92(7):633-5

North S, Moenner M, Bikfalvi A. (2005) Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett. 2005 Jan 31;218(1):1-14.

Shin JW, Min M.,Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L Henderson JE, Bikfalvi A,Detmar M, Hong YK (2006) Prox1 promotes lineage-specific expression of FGF receptor-3 in lymphatic endothelium: A role for FGF signaling in lymphangiogenesis. Mol. Biol Cell 17(2):576-84.

Bikfalvi A (2006) Angiogenesis : health and disease. Ann Oncol. Sep;17 Suppl 10:x65-70.

Caronzolo D, Lucini V, Pannacci M, Grosso S, Kieffer N, Bello L, Bikfalvi A, Scaglione F. Effect of PEX, a noncatalytic metalloproteinase fragment with integrin-binding activity, on experimental Chlamydophila pneumoniae infection. Antimicrob Agents Chemother. 2006, 50(10):3277-82.

W. W. Kilarski and A. Bikfalvi (2006) Recent developments in tumor angiogenesis. Curr Pharm Biotechnol. 2007 Feb;8(1):3-9. Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Canron X, Bikfalvi A, Martuza RL, Kurtz A, Rabkin (2006) Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors.Clin Cancer Res. 12(22):6791-9.

Lasagni L, Grepin R, Mazzinghi B, Lazzeri E, Meini C, Sagrinati C, Liotta F, Frosali F, Ronconi E, Alain- Courtois N, Ballerini L, Netti GS, Maggi E, Annunziato F, Serio M, Romagnani S, Bikfalvi A, Romagnani P. (2007) PF-4/CXCL4 and CXCL4L1 exhibit distinct subcellular localization and a differentially regulated mechanism of secretion. Blood 109(10):4127-34. (Bikfalvi A and P. Romagnani corresponding authors and Co-PI)

Auguste P, Fallavollita L, Wang N, Burnier J, Bikfalvi A, Brodt P. (2007) The host inflammatory response promotes liver metastasis by increasing tumor cell arrest and extravasation. Am J Pathol.170(5):1781-92.

Pisati F, Belicchi M, Acerbi F, Marchesi C, Giussani C, Gavina M, Javerzat S, Hagedorn M, Carrabba G, Lucini V, Gaini SM, Bresolin N, Bello L, Bikfalvi A, Torrente Y. (2007) Effect of human skin-derived stem cells on vessel architecture, tumor growth, and tumor invasion in brain tumor animal models. Cancer Res. 67(7):3054-63.

Drogat B, Bouchecareilh M, North S, Petibois C, Deleris G, Chevet E, Bikfalvi A, Moenner M. (2007) Acute L-glutamine deprivation compromises VEGF-a upregulation in A549/8 human carcinoma cells. J Cell Physiol. 212(2):463-72.

Hagedorn M, Delugin M, Abraldes I, Allain N, Belaud-Rotureau MA, Turmo M, Prigent C, Loiseau H, Bikfalvi A, Javerzat S. (2007) FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients.Cell Div. 2:9-.

Drogat B, Auguste P,Nguyen DT, Bouchecareilh M, Pineau R, Nalbantoglu J, Kaufman RJ, Chevet E, Bikfalvi A, Moenner M (2007) IRE1 Signaling Is Essential for Ischemia-Induced Vascular Endothelial Growth Factor-A Expression and Contributes to Angiogenesis and Tumor Growth In vivo. Can Res. 67(14):6700-7.

Saidi A, Javerzat S, Bellahcène A, De Vos J, Bello L, Castronovo V, Deprez M, Loiseau H, Bikfalvi A, Hagedorn M. (2007) Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma.Int J Cancer 22(10):2187-98.

Petibois C, Drogat B, Bikfalvi A, Déléris G, Moenner M. (2007) Histological mapping of biochemical changes in solid tumors by FT-IR spectral imaging. FEBS Lett. 581(28):5469-74.

Bikfalvi A. [Tumor angiogenesis] (2007) Bull Cancer 94(7 Suppl):F193-8.

Petibois C, Drogat B, Bikfalvi A, Déléris G, Moenner M. (2007) Histological mapping of biochemical changes in solid tumors by FT-IR spectral imaging. FEBS Lett. 581(28):5469-74.

Bikfalvi A. (2007) Angiogenesis: molecular mechanisms of activation, promotion and maintenance. J BUON. Suppl 1:S59-66.

Kilarski W, Bikfalvi A. (2007) [Experimental approaches to study in vivo angiogenesis] Bull Cancer.94 Spec No:S166-9 Hagedorn M., Delugin M., Abraldes I., Allain N., Belaud-Rotureau MA., Turmo M., Prigent C., Loiseau H., Bikfalvi A., Javerzat S.(2007) FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients. Cell Div 2: 9

Navab R, Pedraza C, Fallavollita L, Wang N, Chevet E, Auguste P, Jenna S, You Z, Bikfalvi A, Hu J, O’Connor R, Erickson A, Mort JS, Brodt P. (2008) Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels. Oncogene. 27(37):4973-85.

Bouvrée K, Larrivée B, Lv X, Yuan L, Delafarge B, Freitas C, Mathivet T, Bréant C, Tessier-Lavigne M, Bikfalvi A, Eichmann A, Pardanaud L. (2008) Netrin-1 inhibits sprouting angiogenesis in developing avian embryos. Dev Biol. 318(1):172-83.

Saidi A, Javerzat S, Bellahcène A, De Vos J, Bello L, Castronovo V, Deprez M, Loiseau H, Bikfalvi A, Hagedorn M. (2008) Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma. Int J Cancer 122(10):2187-98.

Aidoudi S, Bujakovska K, Kieffer N, Bikfalvi A (2008) The CXC-Chemokine CXCL4 Interacts With Integrins Implicated In Angiogenesis. PLOSone 3(7):e2657.

Bikfalvi A. Research in France. Science (Careers), 2008, http://www.sciencemag.org/careers/2008/07/person-research-france

Lemiere S Rania A, Gürsel D., Belloc F., Pyronnet S, Bikfalvi A., Auguste P (2008) Overexpression of High Molecular Weight FGF-2 forms inhibits glioma growth by acting on cell cycle progression and protein translation. Exp Cell Res. 314(20):3701-11 (Corresponding Author and CO-PI: A. Bikfalvi)

Bikfalvi A, Ferrara N. Remembering Jean Plouet, a pioneer in angiogenesis reserch in France and co- discoverer of vascular endothelial growth factor. Cancer Res DOI: 10.1126/science.caredit.a0800100Juy 4th 2008

Mykhalchenko VG, Minchenko DO, Tsuchihara K, Moenner M, Komisarenko SV, Bikfalvi A, Esumi H, Minchenko OH. (2008) Expression of mouse 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 mRNA alternative splice variants in hypoxia. Ukr Biokhim Zh. 80(1):19-25.

Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcène A, Verdin E, Castronovo V (2009) HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53- independent mechanism. Oncogene 28(2):243-56.

Ragona L, Tomaselli S, Quemener C, Zetta L, Bikfalvi A. (2009) New insights into the molecular interaction of the C-terminal sequence of CXCL4 with fibroblast growth factor-2. Biochem Biophys Res Commun. 382(1):26-9.

Saidi, A, Hagedorn M, Allain N, Verpelli C., Sala C., Bello L, Bikfalvi A, Javerzat S (2009) Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness. Int J Cancer, 125(5):1054-64.

Javerzat S, Franco M, Herbert J, Platonova N, Peille AL, Pantesco V, De Vos J, Assou S, Bicknell R, Bikfalvi A, Hagedorn M. (2009) Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system. PLoS One 4(11):e7856.

Laklai H, Laval S, Dumartin L, Rochaix P, Hagedorn M, Bikfalvi A, Le Guellec S, Delisle MB, Schally AV, Susini C, Pyronnet S, Bousquet C. (2009) Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer. Proc Natl Acad Sci USA 106(42):17769-74.

Lamour V, Le Mercier M, Lefranc F, Hagedorn M, Javerzat S, Bikfalvi A, Kiss R, Castronovo V, Bellahcène A.(2009) Selective osteopontin knockdown exerts anti-tumoral activity in a human glioblastoma model. Int J Cancer 2010 Apr 15;126(8):1797-805.