Détachée auprès d’une plateforme de prestations de recherche de l’Université
Compétences et thématiques :
- Cycle cellulaire
- Angiogenèse stress et cancer
Biologie cellulaire et immunologie Licences (cours, TD, TP)
Auf G, Jabouille A, Delugin M, Guérit S, Pineau R, North S, Platonova N, Maitre M, Favereaux A, Vajkoczy P, Seno M, Bikfalvi A, Minchenko D, Minchenko O, Moenner M. High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor. BMC Cancer. 2013 Dec 13;13:597. Bikfalvi A, Moenner M, Javerzat S, North S, Hagedorn M. Inhibition of angiogenesis and the angiogenesis/invasion shift. Biochem Soc Trans. 2011 Dec;39(6):1560-4. Dedieu S, Canron X, Rezvani HR, Bouchecareilh M, Mazurier F, Sinisi R, Zanda M, Moenner M, Bikfalvi A, North S. The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A. BMC Med. 2010 Mar 24;8:19 Bianco S, Lanvin O, Tribollet V, Macari C, North S, Vanacker JM. Modulating estrogen receptor-related receptor-alpha activity inhibits cell proliferation. J Biol Chem. 2009 Aug 28;284(35):23286-92. Drogat B, Bouchecareilh M, North S, Petibois C, Déléris G, Chevet E, Bikfalvi A, Moenner M. Acute L-glutamine deprivation compromises VEGF-a upregulation inA549/8 human carcinoma cells. J Cell Physiol. 2007 Aug;212(2):463-72. North S, Moenner M, Bikfalvi A. Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett. 2005 Jan 31;218(1):1-14. Review. Pluquet O, North S, Richard MJ, Hainaut P. Activation of p53 by the cytoprotective aminothiol WR1065: DNA-damage-independent pathway and redox-dependent modulation of p53 DNA-binding activity. Biochem Pharmacol. 2003 Apr 1;65(7):1129-37. Pluquet O, North S, Bhoumik A, Dimas K, Ronai Z, Hainaut P. The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase. J Biol Chem. 2003 Apr 4;278(14):11879-87. Courtois S, Verhaegh G, North S, Luciani MG, Lassus P, Hibner U, Oren M, Hainaut P. DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53. Oncogene. 2002 Oct3;21(44):6722-8. North S, Pluquet O, Maurici D, El-Ghissassi F, Hainaut P. Restoration of wild-type conformation and activity of a temperature-sensitive mutant of p53 (p53(V272M)) by the cytoprotective aminothiol WR1065 in the esophageal cancer cell line TE-1. Mol Carcinog. 2002 Mar;33(3):181-8 Maurici D, Monti P, Campomenosi P, North S, Frebourg T, Fronza G, Hainaut P. Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay. Oncogene. 2001 Jun 14;20(27):3533-40 North S, Hainaut P. p53 and cell-cycle control: a finger in every pie. Pathol Biol (Paris). 2000 Apr;48(3):255-70. Review. North S, El-Ghissassi F, Pluquet O, Verhaegh G, Hainaut P. The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progressionthrough a p53-dependent pathway. Oncogene. 2000 Feb 24;19(9):1206-14. North S, Espanel X, Bantignies F, Viollet B, Vallet V, Jalinot P, Brun G, Gillet G. Regulation of cdc2 gene expression by the upstream stimulatory factors (USFs). Oncogene. 1999 Mar 18;18(11):1945-55. Espanel X, Le Cam L, North S, Sardet C, Brun G, Gillet G. Regulation of E2F-1 gene expression in avian cells. Oncogene. 1998 Aug 6;17(5):585-94. Michel D, Chatelain G, North S, Brun G. Stress-induced transcription of the clusterin/apoJ gene. Biochem J. 1997 Nov 15;328 ( Pt 1):45-50. North S, Espanel X, Tavitian B, Brun G, Gillet G. Two distinct regulatory elements control quail cdc2 transcription: possible involvement in the control of retinoblast differentiation. Cell Growth Differ. 1996 Mar;7(3):339-49