Licence Professionnelle Biologie Analytique et Expérimentale
Impliqué dans le projet “Glioblastome”
Culture cellulaire
- Niveaux de confinement I et II
- Infections virales
- Transfections
- ARN interférents
- Tests In Vitro (prolifération, migration, invasion)
Biochimie
- Western Blot
- Immunoprécipitation
- PLA
- Immunohistochimie / immunocytochimie / colorations histologiques
Imagerie
- Microscopie optique et à fluorescence
- Microscopie Confocale
- Vidéomicroscopie
In vivo
- Habilitation à l’expérimentation animale niveau II
- Chirurgie
- Autopsies
The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors. Boyé K, Pujol N, D Alves I, Chen YP, Daubon T, Lee YZ, Dedieu S, Constantin M, Bello L, Rossi M, Bjerkvig R, Sue SC, Bikfalvi A, Billottet C. Nat Commun. 2017 Nov 17;8(1):1571. doi: 10.1038/s41467-017-01686-y. PMID:29146996
Oligomerization State of CXCL4 Chemokines Regulates G Protein-Coupled Receptor Activation. Chen YP, Wu HL, Boyé K, Pan CY, Chen YC, Pujol N, Lin CW, Chiu LY, Billottet C, Alves ID, Bikfalvi A, Sue SC. ACS Chem Biol. 2017 Nov 17;12(11):2767-2778. doi: 10.1021/acschembio.7b00704. Epub 2017 Oct 4. PMID:28945356
Ligand activation induces different conformational changes in CXCR3 receptor isoforms as evidenced by plasmon waveguide resonance (PWR). Boyé K, Billottet C, Pujol N, Alves ID, Bikfalvi A. Sci Rep. 2017 Sep 6;7(1):10703. doi: 10.1038/s41598-017-11151-x. PMID: 28878333
Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5. Exertier P, Javerzat S, Wang B, Franco M, Herbert J, Platonova N, Winandy M, Pujol N, Nivelles O, Ormenese S, Godard V, Becker J, Bicknell R, Pineau R, Wilting J, Bikfalvi A, Hagedorn M. Oncotarget. 2013 Dec;4(12):2302-16. PMID: 24327603